Antimicrobial resistance: Nurse’s knowledge and perception in a tertiary level care hospital in North-Eastern Nigeria
Accepted: April 11, 2021
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Nursing staff has a significant role to play in the control of Antimicrobial Resistance (AMR) through infection control and patient education. We studied the knowledge of nurses on AMR for purpose of planning AMR control efforts. A cross-sectional study was conducted between 21st June and 30th July 2017, among nurses working at Federal Medical Center Nguru, Yobe State. Responses were presented as frequencies and percentages. Relative risks and 95% confidence intervals were computed to describe factors associated with knowledge of AMR. Only 37.2% of the respondents had good knowledge of AMR. Age more than or equal to 40 years versus less than 40 years (RR=2.66, 95% CI: 1.253-5.662), work experience greater than or equal to 10 years versus less than 10 years (RR=2.94, 95% CI: 1.518-5.686) predicted good knowledge of AMR. A significant knowledge gap on AMR among nurses has been identified. We recommend a robust AMR awareness initiative to educate nursing staff on AMR. Further studies among other cadre of healthcare workers should be conducted to define and address the AMR knowledge gap among all Nigerian healthcare workforces.
Greenwood D. Antimicrobial drugs: chronicle of a twentieth century medical triumph: Oxford University Press; 2008.
Friedman ND, Temkin E, Carmeli Y. The negative impact of antibiotic resistance. Clin Microbiol Infect 2016;22:416-22. DOI: https://doi.org/10.1016/j.cmi.2015.12.002
Jasovský D, Littmann J, Zorzet A, Cars O. Antimicrobial resistance—a threat to the world’s sustainable development. Ups J Med Sci 2016;121:159-64. DOI: https://doi.org/10.1080/03009734.2016.1195900
Tagliabue A, Rappuoli R. Changing priorities in vaccinology: antibiotic resistance moving to the top. Front Immunol 2018;9:1068. DOI: https://doi.org/10.3389/fimmu.2018.01068
WHO. Global antimicrobial resistance surveillance system (GLASS) report: early implementation 2016-2017. WHO: Geneva: 2017. Available from: https://www.who.int/glass/resources/publications/early-implementation-report/en/
O'Neill J. Tackling drug-resistant infections globally: final report and recommendations. 2016. HM Government and Welcome Trust: UK 2018. Available from: https://apo.org.au/sites/default/files/resource-files/2016-05/apo-nid63983.pdf
Dunachie SJ, Day NP, Dolecek C. The challenges of estimating the human global burden of disease of antimicrobial resistant bacteria. Curr Opin Microbiol 2020;57:95-101. DOI: https://doi.org/10.1016/j.mib.2020.09.013
Babatola AO, Fadare JO, Olatunya OS, et al. Addressing antimicrobial resistance in Nigerian hospitals: exploring physicians prescribing behavior, knowledge, and perception of antimicrobial resistance and stewardship programs. Expert Rev Anti Infect Ther 2020:1-10. DOI: https://doi.org/10.1080/14787210.2021.1829474
Chowdhury MMH, Kubra K, Islam MT, et al. Indiscriminate uses of antibiotics as a threat to public health demand implementation of effective drug practices and enhancement of public awareness in Bangladesh. Eur J Sci Res 2015;133:187-95.
Cosgrove SE. The relationship between antimicrobial resistance and patient outcomes: mortality, length of hospital stay, and health care costs. Clin Infect Dis 2006;42:S82-S9. DOI: https://doi.org/10.1086/499406
Chukwu EE, Oladele DA, Awoderu OB, et al. A national survey of public awareness of antimicrobial resistance in Nigeria. Antimicrob Resist Infect Control 2020;9:1-10. DOI: https://doi.org/10.1186/s13756-020-00739-0
Ajibola O, Omisakin OA, Eze AA, Omoleke SA. Self-medication with antibiotics, attitude and knowledge of antibiotic resistance among community residents and undergraduate students in Northwest Nigeria. Diseases 2018;6:32. DOI: https://doi.org/10.3390/diseases6020032
Dyar OJ, Pulcini C. The roles of nurses in antimicrobial stewardship. Antimicrobial Stewardship: Elsevier; 2017: p. 139-45. DOI: https://doi.org/10.1016/B978-0-12-810477-4.00011-8
Abera B, Kibret M, Mulu W. Knowledge and beliefs on antimicrobial resistance among physicians and nurses in hospitals in Amhara Region, Ethiopia. BMC Pharmacol Toxico 2014;15:1-7. DOI: https://doi.org/10.1186/2050-6511-15-26
García C, Llamocca LP, García K, et al. Knowledge, attitudes and practice survey about antimicrobial resistance and prescribing among physicians in a hospital setting in Lima, Peru. BMC Clin Pharmacol 2011;11:1-8. DOI: https://doi.org/10.1186/1472-6904-11-18
Pearson M, Chandler C. Knowing antimicrobial resistance in practice: a multi-country qualitative study with human and animal healthcare professionals. Glob health action 2019;12:1599560. DOI: https://doi.org/10.1080/16549716.2019.1599560
Abbo L, Smith L, Pereyra M, et al. Nurse practitioners' attitudes, perceptions, and knowledge about antimicrobial stewardship. J Nurse Pract 2012;8:370-6. DOI: https://doi.org/10.1016/j.nurpra.2012.01.023
Abdel-Qader DH, Albassam A, Ismael NS, et al. Community pharmacists’ knowledge of and attitudes toward antibiotic use, resistance, and self-medication in Jordan. Drugs Ther Perspect 2021;37:44-53. DOI: https://doi.org/10.1007/s40267-020-00797-9
Moura JPd, Gir E. Nursing staff knowledge of multi-resistant bacterial infections. Acta Paul Enferm 2007;20:351-6. DOI: https://doi.org/10.1590/S0103-21002007000300018
Azevedo MM, Pinheiro C, Yaphe J, Baltazar F. Portuguese students' knowledge of antibiotics: a cross-sectional study of secondary school and university students in Braga. BMC Public Health 2009;9:1-6. DOI: https://doi.org/10.1186/1471-2458-9-359
Fadare JO, Ogunleye O, Iliyasu G, et al. Status of antimicrobial stewardship programmes in Nigerian tertiary healthcare facilities: findings and implications. J Glob Antimicrob Resist 2019;17:132-6. DOI: https://doi.org/10.1016/j.jgar.2018.11.025
Gillespie E, Rodrigues A, Wright L, et al. Improving antibiotic stewardship by involving nurses. Am J Infect Control 2013;41:365-7. DOI: https://doi.org/10.1016/j.ajic.2012.04.336
Dayyab FM, Iliyasu G, Habib AG. Adherence to HIV Postexposure Prophylaxis in a Major Hospital in Northwestern Nigeria. Infect Control Hosp Epidemiol 2018;39:247-8. DOI: https://doi.org/10.1017/ice.2017.276
Huang Y, Gu J, Zhang M, et al. Knowledge, attitude and practice of antibiotics: a questionnaire study among 2500 Chinese students. BMC Med Educ 2013;13:1-9. DOI: https://doi.org/10.1186/1472-6920-13-163
Dayyab FM, Iliyasu G, Ahmad BG, et al. Hepatitis B vaccine knowledge and self-reported vaccination status among healthcare workers in a conflict region in northeastern Nigeria. Ther Adv Vaccines Immunother 2020;8:2515135519900743. DOI: https://doi.org/10.1177/2515135519900743
Iliyasu G, Dayyab FM, Habib ZG, et al. Knowledge and practices of infection control among healthcare workers in a Tertiary Referral Center in North-Western Nigeria. Ann Afr Med 2016;15:34. DOI: https://doi.org/10.4103/1596-3519.161724
Dayyab FM, Iliyasu G, Aminu A, et al. A prospective study of hospital-acquired infections among adults in a tertiary hospital in north-western Nigeria. Trans R Soc Trop Med Hyg 2018;112:36-42. DOI: https://doi.org/10.1093/trstmh/try020
Iliyasu G, Dayyab FM, Aminu A, et al. Epidemiology and Microbiology of Bacterial Bloodstream Infection in a Tertiary Hospital in Nigeria. Infect Dis Clin Pract 2020;28:16-21. DOI: https://doi.org/10.1097/IPC.0000000000000783
Reviriego E, Cidoncha MÁ, Asua J, et al. Online training course on critical appraisal for nurses: adaptation and assessment. BMC Med Educ 2014;14:1-10. DOI: https://doi.org/10.1186/1472-6920-14-136
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.