Bone marrow aspiration cytology in Abubakar Tafawa Balewa University Teaching Hospital, Bauchi State, Nigeria: Indications and diagnostic utility


Published: July 1, 2019
Abstract Views: 487
PDF: 271
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • Rufai Abdu Dachi Department of Hematology and Blood Transfusion, Abubakar Tafawa Balewa University Teaching Hospital Bauchi, Nigeria.
  • Falmata Grema Mustapha Department of Hematology and Blood Transfusion, Abubakar Tafawa Balewa University Teaching Hospital Bauchi, Nigeria.
  • Saleh Yuguda Department of Hematology and Blood Transfusion, Federal Teaching Hospital, Gombe, Nigeria.
  • Modu Baba Kagu Department of Hematology and Blood Transfusion, University of Maiduguri Teaching Hospital Maiduguri, Nigeria.
  • Ali Adamu Gwaram Department of Hematology and Blood Transfusion, Abubakar Tafawa Balewa University Teaching Hospital Bauchi, Nigeria.
  • Philemon Bwala Department of Hematology and Blood Transfusion, Abubakar Tafawa Balewa University Teaching Hospital Bauchi, Nigeria.

Bone Marrow Aspiration (BMA) cytology is an important diagnostic and monitoring tool where cytological details of the marrow elements are examined using light microscopy. Various hematological diseases are diagnosed and monitored by using BMA. This study aimed at reporting a 3-year BMA experience of Department of Hematology and Blood Transfusion of Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH) Bauchi. This was a retrospective study that involved the use of records of the bone marrow aspirates done from January 1st, 2016 to December 31st, 2018. The age, sex, indications for BMA, anatomical site and final bone marrow diagnosis were collated. The data was analyzed using SPSS Version 23.0 software. One hundred and three (103) bone marrow aspirations were performed during the period under review. Two third of the participants were males, with the median age of 40.0 years and a range of 5 months to 92 years. The commonest indication for BMA was recurrent anemia 45.6%, followed by splenomegaly, fever and lymphadenopathy with 11.7% each. While, the commonest diagnosis by BMA was megaloblastic anemia (28.2%). Mixed nutritional deficiency and Bone Marrow (BM) metastasis are the commoner BMA diagnoses with 12.6% each. Recurrent anemia is the commonest indication for BMA and nutritional anemias (megaloblastic and combined nutrients deficiency) are the commonest BMA diagnoses in Bauchi. Proper evaluation of patients by the clinicians before referral is recommended to ensure that only those that really need the procedure are subjected to it.


Bates I, Burthem J. Bone marrow biopsy. In Dacie and Lewis Practical Haematology. 11th ed. Churchil Livingstone Inc Philadelphia.2012; (7);123-137. DOI: https://doi.org/10.1016/B978-0-7020-3408-4.00007-2

Dzierzak E. Stem cells and haemopoiesis. In: Hoffbrand A, Catovsky D, Tuddenham E, editors. Postgraduate Haematology. 6th ed. Massachusetts USA: Blackwell Publishers Ltd; 2011;(1):1–11. DOI: https://doi.org/10.1002/9781444323160.ch1

Ryan DH, Cohen HJ. Bone Marrow Aspiration and Morphology. In: Haematology: Basic Principles and Practice. 3rd ed. Churchil Livingstone Inc Philadelphia; 2000.

Berber I, Erkurt MA, Kuku I, Kaya E, Kutlu R, Koroglu M, et al. An unexpected complication of Bone Marrow Aspiration and Trephine Biopsy: Arteriovenous Fistula. Med Princ and Pract 2014;223:280-383. DOI: https://doi.org/10.1159/000358173

Lee SH, Erber WN, Porwit A, Tomonaga M, Peterson IC. ICSH guidelines for the standardization of bone marrow specimens and reports. Int Jnl. Lab. Hem.2008; 30:349-364.

Awwalu S, Hassan A, Dogara LG, Musa AU, Waziri AD, Babadoko AA. Bone Marrow Aspiration (BMA) in Zaria: A 3 year retrospective review. Borno Medical Journal. 2016; 3(1). 54-55.

Egesie OJ, Joseph DE, Egesie UG, Ewuga OJ. Epidemiology of anaemia necessitating Bone Marrow aspiration cytology in Jos. Nig Med Jnl. 2010; 50(3): 61-63.

Khan SP, Sajjad G, Shareefa A, Shuaeb B, Saleem H, Fahin M et al. Bone marrow aspiration in haematological disorders: study at a tertiary care centre. Int Jnl of Research in Med Sci. 2018; 6(7): 2363. DOI: https://doi.org/10.18203/2320-6012.ijrms20182817

Gohli M, Kruti R. Bone marrow aspiration cytology study in a tertiary care centre, Gujurat, India. Int Jnl Sci Study, 2018; 5: 12-13.

Elmadhoun WM, Noor SK, Ahmed MH, Bushara SO, Husain NE, Ahmed MH. Bone marrow aspiration in north Sudan: the procedure, indications and the diagnostic value. Int Jnl of Health Sci, 2015; 9(4):435-439. DOI: https://doi.org/10.12816/0031233

Bedu-Addo G, Ampem Amoako Y, Bates I. the role of bone marrow aspiration and trephine samples in haematological diagnosis in patients referred to a teaching hospital in Ghana, Ghanian Medical Journal, 2013; 47(2): 74-78.

Adewoyin AS, Ezire ES, Adeyemi O, Idubor NT, Edewor-Okiyo DO. Bone marrow aspiration cytology studies in a Tertiary Hospital Nigeria: A seires of 88 cases. Annals of Pathology and Lab. Med, 2015; 2 (4): 107-114.

Kawthalkar SM. Overview of Physiology of Blood. Normal haematopoiesis. In: Essentials of Haematology. 2nd ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2013; (1):1-51. DOI: https://doi.org/10.5005/jp/books/11810_1

Damulak OD, Damen JG. Diagnostic outcome of Bone marrow aspiration in a new centre in Nigeria. Global Advanced Research Jnl of Med and Med Sci. 2012; 1(7): 166- 171.

Nigeria Poverty Profile. Federal Republic of Nigeria: Poverty Indicators. 2010;2:6.

Hypochromic aneamias. In Hoffbrand AV, Moses PAH, Petit JE. Essential Haematology. 7th ed, 2016. 3: Pp28.

Dachi, Rufai Abdu, Falmata Grema Mustapha, Saleh Yuguda, Modu Baba Kagu, Ali Adamu Gwaram, and Philemon Bwala. 2019. “Bone Marrow Aspiration Cytology in Abubakar Tafawa Balewa University Teaching Hospital, Bauchi State, Nigeria: Indications and Diagnostic Utility”. Annals of African Medical Research 2 (1). https://doi.org/10.4081/aamr.2019.72.

Downloads

Download data is not yet available.

Citations